Heart Transplantation.

AUTHOR INFORMATION

James K. Kirklin, MD, Professor of Surgery, Director of Cardiothoracic Transplantation, UAB Endowed Professor of Cardiovascular Surgical Research, Division of Cardiothoracic Surgery, University of Alabama at Birmingham Medical Center, Birmingham, AL;

James B. Young, MD, Medical Director, Kauffman Center for Heart Failure, Head, Section of Heart Failure and Cardiac Transplant Medicine, Department of Cardiology ,Cleveland Clinic Foundation, Cleveland, OH; and

David C. McGiffin, MD, Professor Surgery, Division of Cardiothoracic Surgery, Department of Surgery, University of Alabama at Birmingham Medical Center, Birmingham, AL

TABLE OF CONTENTS

1. History of Cardiac Transplantation
2. Immunology in Relation to Cardiac Transplantation
3. Methodology for Clinical Research in Cardiac Transplantation

The Patient Before Transplantation

4. Pathophysiology and Clinical Features of Heart Failure
5. Medical and Nontransplant Surgical Therapy of Heart Failure
6. Recipient Evaluation and Selection
7. Pretransplant Immunologic Evaluation and Management
8. Mechanical Support of the Failing Heart

The Transplanted Heart

9. The Donor Heart
10. The Heart Transplant Operation
11. Physiology of the Transplanted Heart

Management of the Transplant Patient

12. Management of the Recipient During the Transplant Hospitalization
13. Immunosuppressive Modalities
14. Cardiac Allograft Rejection
15. Infections after Heart (and Heart/Lung) Transplantation

Long-Term Outcome after Heart Transplantation

16. Survival after Heart Transplantation
17. Cardiac Allograft Vasculopathy (Chronic Rejection)
18. Other Long-Term Complications
19. Quality of Life After Heart Transplantation

Special Situations in Heart Transplantation

20. Pediatric Heart Transplantation
21. Combined Heart and Other Organ Transplantation
22. Cardiac Retransplantation
23. Xenotransplantation
24. Resource Allocation in Heart Transplantation